By TheBloodApp Team·

How Blood Banks Store And Preserve Donated Blood In India

Lab technician places labeled blood samples in refrigerator for safe preservation.

A laboratory technician is inside a medical refrigerator, organizing blood containers.

Blood banks are an indispensable part of the health care system; they help in providing the correct and sufficient amount of blood to patients in emergencies and other needs. Storage and maintenance of blood donated in blood banks in India are carried out under medical, governmental, and technical requirements to keep the blood in good health and appropriate condition.

Procedures such as blood collection, testing, separation of components, and storage in blood banks in India are carefully monitored to prevent bacterial and other infections and increase the shelf life of blood. Furthermore, various modern techniques are used in the blood bank for its storage.

The working of blood banks across the world can be well understood from this, helping all to save blood and help people suffering from chronic diseases like cancer, etc., and who require blood at times.

Significance Of Proper Blood Storage

All blood samples must be stored in conditions that keep them safe, stable, and efficient for both clinical and research use. Without such conditions, it is possible that blood will break down, resulting in erroneous results and possibly dangers in a blood transfusion. Once blood has been collected, it is further processed to ensure each of its parts remains in the best conditions for its specific function and use.

Components And Storage Requirements

  • Red blood cells need to be stored at refrigerated temperatures to retain their ability to transport oxygen.
  • Plasma needs to be stored frozen to keep the clotting factors and proteins working correctly.
  • Platelets need to be stored at room temperature and mixed at all times to maintain their viability.
  • White blood cells often need to be stored under unique or cryogenic temperatures, depending on how they are going to be used and researched.

Effective storage is crucial to the quality and integrity of blood components, thus protecting patients and effective medical therapies.

How Does The Blood Bank Store Blood?

1. Collection And Pre-Screening Of Donated Blood

The blood bank collects blood from voluntary donors in sterile blood bags with the added anticoagulant. Donated blood is pre-screened for infections like Hepatitis B and C, HIV, Syphilis, and Malaria for transfusion safety.

2. Blood Grouping And Cross-Matching

Blood is classified based on the ABO and Rh blood grouping system and cross-matched to ensure compatibility between the donor's blood and the patient's blood for transfusion.

3. Separation Into Blood Components

Whole blood is centrifuged at high speed, which separates it into red blood cells, plasma, and platelets, to serve the specific requirement of the patient, to be transfused or processed for other derivatives.

4. Storage And Preservation

Red cells are stored at 2 - 6 °C in preservative solution (such as CPDA-1 or SAGM) until expiry. Platelets are stored at 20 - 24 °C with constant agitation, and plasma is stored at -30 °C or below.

5. Shelf Life And Quality Control

Red cells are stored for up to 42 days, whereas platelets are stored for about 5 - 7 days and plasma for up to a year. Blood is continually monitored for storage conditions and quality before it is released for transfusion.

A health care worker in gloves is inserting a blood collection tube into a rack to obtain a sample for clinical testing.

A lab technician is holding and organizing test tubes with red caps, with proper labels for lab use for testing

Temperature Requirements To Maintain Blood Safety

An important part of storing blood properly and making sure it stays safe and viable is its correct storage temperature. Each blood product has its own storage requirements. Whole blood and red blood cells require storage in a medical-grade blood bank refrigerator where the temperature must be maintained between +2°C and +6°C, with optimal storage being around +4°C.

Platelets, in contrast, need to be stored at +20°C to +24°C with constant gentle agitation. Plasma and cryoprecipitate need to be stored as a frozen product below -30°C to keep clotting factors functional.

Temperatures must be maintained consistently within a certified storage appliance, which needs to be fitted with appropriate alarms to alert staff of any significant temperature deviations. This temperature regulation is highly regulated and crucial to the safety of patients.

Storage Duration Of Each Blood Component

Shelf life is determined by the component, provided that storage conditions are followed:

  • Red blood cells can generally be stored up to 42 days when stored between +2°C and +6°C.
  • Platelets are much shorter lasting; they are stored between +20°C and +24°C for 5–7 days when gently but continuously agitated to ensure function.
  • Frozen plasma can be stored up to 12 months when frozen to -30°C or lower, and cryoprecipitate lasts up to 1 year, also when frozen to -30°C or lower. Both storage types can only be stored for this length of time when temperature control is constantly maintained.

Equipment Solutions To Aid Blood Bank Storage

1. Blood Bank Refrigerators

Refrigerators are designed for storing whole blood and red blood cells at a controlled temperature of usually +2 to +6 °C. The design provides an even temperature distribution and adequate circulation of cold air and a warning system to ensure the blood is not exposed to undesirable temperatures.

2. Plasma And Laboratory Freezers

Plasma and other frozen blood components need to be stored in a freezer at –30°C or less; they have a tendency to retain their factors and protein content over long periods.

3. Ultra-Low Temperature Freezers

These are able to store materials at temperatures as low as -86°C, and usually at a very unique level, these store the specific materials in special conditions and are used for longer-term storage.

4. Temperature Monitoring Systems

There are continuous systems that monitor the stored temperature and alert systems that warn you if the temperature exceeds what it should be stored at, and they are also recorded on logging systems to conform to standards.

Final Thought

Blood banks, in the field of health care services, contribute to providing continuous access to the safe, potent blood necessary for routine as well as emergency transfusions. Right from the donation, collection, testing, and fractionation, each step of blood is monitored scientifically under stringent guidelines.

Maintaining the precise storage temperatures for each blood component and using advanced equipment are critical in preventing bacterial growth and functional decline. By adhering to precise temperature controls and rigorous monitoring techniques, blood banks in India guarantee that the transfused blood is always of the highest possible quality, ultimately contributing to the saving and betterment of lives.

Person donating blood, squeezing a stress ball while blood flows into an IV line attached to a blood collection device in a hospital setting.

Closeup of an arm with a blood collection tube in it, with an IV connected and the blood bag set on the chair next to it.

References

1. Arctiko: https://arctiko.com/blood-bank-storage/?srsltid=AfmBOor9ggGX3rpA1Oy3lEiXyut-sHbJttMwVoyefzxc_yNKrDsb5hHZ

2. Froilabo: https://www.froilabo.com/blog/blood-storage-and-preservation/

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